Various growth factors secreted from ASCs, including VEGF, HGF, bFGF, and IGF-1, are associated with neuroprotective effects or enhancement of neurogenesis [11], [21], [26], [27] and FGF-2 and IGF-1 have proven to be beneficial in experimental models of HD [28], [29]. The gene discussed is IGF1; the disease is Huntington disease.