GPT and dengue disease: In the past, several small studies have shown no effect of HBV infection on acute dengue morbidity,14,15 but our findings are in agreement with a recent study in which nearly 400 patients with dengue-1 virus infection were studied and showed slightly greater increases in ALT levels among patients with HBV co-infection.23 We found no clinically significant effects in our study, but the possibility that repeated dengue infections may alter the rate of progression of the HBV infection needs to be considered.