PLA2G6 and Parkinsonism: Since PLA2G6 has also been observed to hydrolyze palmitoyl coenzyme A (CoA) in vitro [9], we examined PLA2G6 catalytic activity using radiolabeled palmitoyl CoA, and observed that the dystonia-parkinsonism mutations also do not impair PLA2G6 thioesterase activity (Figure S1).