Significantly, in both MBP and anti-CD3 stimulated MS-derived cells, PP14·Fcγ1 significantly inhibited both IFN-γ and IL-17 secretion (Fig. S1, C and D, respectively), suggesting it's capability to inhibit these cytokines in both normal and MS pathological conditions despite the predominant Th17 response in the latter. This evidence concerns the gene MBP and myeloid sarcoma.