CLEC7A and fungal infectious disease: In view of the complexity and the structural differences in the fungal cell wall of fungi [31], [32], whether activation of dectin-1 signaling is a major pathway for TH-17 induction in response to airborne opportunistic fungal pathogens that currently cause the majority of fungal infections in immunocompromised patients, and whether this ability is related to specific growth stages and/or the inherent pathogenic behavior of each fungus in currently unknown.