CCL2 and infectious otitis media: To further understand the inflammatory milieu in the colons of mice during early tumorigenesis in our experimental model, we measured the expression of various chemokines in the colonic tissue, including MCP-1 (CCL2), KC (CXCL1), MIP-2 (CXCL2) and RANTES (CCL5), at day 14 of AOM-DSS treatment.