The aim of the present study was to investigate the expression of SP17 and NY-ESO-1 and overexpression of p53, WT1, and survivin together with β2-microglobulin and the α-chains, HLA-A and HLA-B/C, in tumor samples obtained from a large well-documented cohort of primary EOC patients using tissue microarray. This evidence concerns the gene TP53 and neoplasm.