SNPs within three of the gene fifteen genes replicated in two or more studies were associated with accelerated progression to AIDS-1987 in the current study: NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7 (NDUFB7), Isocitrate Dehydrogenase 1 (IDH1) , and Isocitrate Dehydrogenase 3 (NAD+) Alpha (IDH3A)] (NDUFB7 rs6511939 HR = 1.6, p = 0.008; IDH1 rs7580715 HR = 2.1, p = 0.009, IDH3A rs11855354, rs8032618 and rs12903696 HR = 1.6, p = 0.007–0.009). This evidence concerns the gene IDH3A and AIDS.