SNPs within three of fifteen genes replicated between the original studies were associated with accelerated progression to AIDS-1987 in the current study: NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7 (NDUFB7), Isocitrate Dehydrogenase 1 (IDH1) , and Isocitrate Dehydrogenase 3 (NAD+) Alpha (IDH3A)]. The gene discussed is NDUFB7; the disease is AIDS.