There are studies where Ki-67 labeling index (LI) appears as an independent prognostic factor prostate cancer.[20] Moul et al, have stated that, patients with a high MIB-1 score -a monoclonal antibody to recombinant parts of Ki-67- experienced recurrence 3.1 times more than others.[21] We have observed a high (over 10%) Ki-67 LI in 10% of our tumors. This evidence concerns the gene MKI67 and prostate cancer.