BRCA2 and neoplasm: Gains in the regions 1q32–q41, 8q22.1–24.3, and 20q12–q13, and loss in the region 8p23.3–p21.2 occur in both the primary and xenograft tumours and have also been found in primary BRCA2 tumours by different authors (Gronwald et al, 2005; Jonsson et al, 2005).