Moreover, peptides of the CRF family and their receptors have been also found expressed by several cancer cells [12], such as human renal cell carcinoma [13], tumorous adrenocortical cells [14], human endometrial, prostate, ovarian and breast cancer cells [14-19], human pheochromocytoma cells and melanomas [20-22] and the murine melanoma cell line B16F10 [23]. The gene discussed is CRH; the disease is cancer.