The direct promotion of cancer cell survival and the inflammation-induced chemoresistance have been linked to the hyperactivation of NF-κB in cancer cells, which induces upregulation of antiapoptotic proteins such as c-FLIP and XIAP, and inhibition of proapoptotic proteins such as Bax and Caspase-9 [42, 43]. This evidence concerns the gene NFKB1 and cancer.