Using two doses of EerI (1 mM and 10 mM), we found that partial VCP/ERAD inhibition potently suppressed retinal degeneration in Rh1P37H;Rh1+/+ flies after 30 dle (Figure 6B–6D and 6G; n>7 flies/genotype). This evidence concerns the gene VCP and retinal degeneration.