Infection with any of these nematodes is associated with a strong polarization of the host’s immune response towards Th2, with prominent secretion of IL‐4 and IL‐5 and elevated levels of IgG4 and IgE (Hussain et al., 1981; Ottesen et al., 1985; Hussain and Ottesen, 1986; Mahanty et al., 1993). Here, IGHE is linked to infection.