Consistent with a role for early and late endosomes and in contrast to the lack of effect of DN Eps15 and Cav-1 expression, GFP-tagged DN Rab5 or DN-Rab7 resulted in significant reduction (P<0.001 for each) in infection by gfpZEBOV (Fig. 6C). The gene discussed is CAV1; the disease is infection.