Patient gender and sex, preoperative AFP (with a cutoff set at 30 ng/mL, according to our previous experience) [7, 16], type of viral infection, fulfilling of MC at OLT, preoperative treatments, preoperative down-staging, fulfilling of MC at final histology of the explanted native liver, tumor differentiation, presence of micro- and macrovascular tumor invasion, and postoperative immunosuppression including m-TOR inhibitors were all analyzed for their impact on RFS. Here, AFP is linked to viral infectious disease.