IMP1 expression is stimulated by Wnt/β-catenin signaling and has many regulatory targets, some of which are implicated in cancer: stabilization of c-myc [34,35] and CD44 mRNAs [36], translational suppression of IGF2 [37], and localization of β-actin mRNA to sites of actin polymerization [38]. The gene discussed is IGF2BP1; the disease is cancer.