There was weak evidence of association between rs9939609 and other obesity-related metabolic traits including TC (3.92 ± 0.03 mmol/L vs. 4.02 ± 0.05 mmol/L, P = 0.10), insulin (2.69 ± 1.77 ng/ml vs. 3.12 ± 2.91 ng/ml, P = 0.14), and insulin resistance (HOMA-IR 0.56 ± 0.03 vs. 0.66 ± 0.05, P = 0.10), Table 4. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.