Since all antibodies screened that antagonize signaling in Wnt3a-stimulated HEK293 cells also inhibit Wnt3a stimulation in all other cell lines tested, and also inhibit autocrine Wnt signaling in teratocarcinoma cell lines, it was intriguing that these antibodies potentiate autocrine Wnt signaling in the other nine cell lines tested. This evidence concerns the gene WNT3A and teratocarcinoma.