In NCI-H23 NSCLC cells and in M14 melanoma cells, potentiation of autocrine Wnt signaling by YW211.31 antibody and antagonism by YW210.09 are consistent with Wnt2 RNAi inhibiting endogenous signaling in NCI-H23 cells [23], and with endogenous Wnt1 expression in M14 cells [35]. This evidence concerns the gene WNT1 and non-small cell lung carcinoma.