The olfactory pathway represents then a very useful neuronal circuit to test hypothesis concerning (1) the mechanisms of STOP protein functions at the synapse, (2) neuronal connectivity disturbances as pathophysiological mechanisms involved in developmentally induced synaptic connectivity disturbance and altered neurogenesis in schizophrenia, (3) new therapies for proof of concept for future human treatment [46]–[48]. This evidence concerns the gene MAP6 and schizophrenia.