For those with the AT1R A1166C AA genotype, individuals with the BDKRB2 C58T TT or BDKRB2 C58T CT genotypes had a significantly higher hazard of cardiovascular disease as compared to those who carried the BDKRB2 C58T CC genotype (adjusted HR = 1.67, 95% CI: 1.04–2.70). The gene discussed is BDKRB2; the disease is cardiovascular disorder.