MUTYH and polyp of large intestine: All of the above are MUTYH variants that have been identified in patients with colorectal polyposis and/or with colorectal cancer (Halford et al., 2003; Sieber et al., 2003; Aceto et al., 2005; Aretz et al., 2006; Kanter-Smoler et al., 2006; Lejeune et al., 2006; Peterlongo et al., 2006; Russell et al., 2006; Yanaru-Fujisawa et al., 2008).