With regard to structure and expression profiles, the most interesting gene related to FOXP1 is FOXP2. Rare mutations of FOXP2 have been described in individuals having expressive and receptive language and speech deficits generally described as developmental verbal dyspraxia (Hurst, et al., 1990; Lai, et al., 2001; MacDermot, et al., 2005; Marshall, et al., 2008). The gene discussed is FOXP1; the disease is childhood apraxia of speech.