MIF plasma levels decreased significantly within 48 hours after sepsis onset (t0 → t24: P = .050*, t24 → t48: P = .893, t0 → t48: P = .028*), but still remained significantly elevated than the volunteer group (t24: P = .030*, t48: P = .048*) and the postoperative group (t24: P = .023*, t48: P = .069) (Figure 3). This evidence concerns the gene MIF and Sepsis.