For IL-8, mRNA level was higher in TU than in NTU in all groups of CRC patients; IL-8 mRNA was higher in TU and NTU of SGMB+ve groups in both CRC-w/bac and CRC-wo/bac than in SGMB-ve groups; and IL-8 mRNA was higher in TU and NTU of SGMB+ve, but not SGMB-ve, in both CRC-w/bac and CRC-wo/bac than in control group (Figure 3 and 4). The gene discussed is CXCL8; the disease is colorectal carcinoma.