IL1B and colorectal carcinoma: On the other hand, the mRNA level of proinflammatory cytokines, IL-1 and COX-2, was at close levels between TU and NTU of all CRC groups; it was significantly higher in TU and NTU of SGMB+ve than in SGMB-ve groups in both CRC-w/bac and CRC-wo/bac; and it was higher in TU and NTU of SGMB+ve, but not SGMB-ve, groups than in control group (Figure 3 and 4).