We observed a higher expression of CD4+ NKT cells in CVID patients when compared to healthy controls [81.40 (30.80–97.00), and 26.10 (20.95–39.55), respectively, p = 0.0055](Figure 3 A,B,C), although these appeared to cluster in a high CD4+ expression group, and a lower CD4+ expression group. The gene discussed is CD4; the disease is common variable immunodeficiency.