According to the IHC scoring system, 16 cases (8/20 NSCLC and 8/13 pulmonary mCRC) showed an intense EGFR-immunoreactivity (score 3+) (fig 2), 5 moderate reactivity (score 2+) and 3 weak reactivity (score 1+). This evidence concerns the gene EGFR and non-small cell lung carcinoma.