CCND1 and neoplasm: Recent studies have revealed that the Wnt-1 overexpression, resulting in an aberrant and stabilized β-catenin expression, is associated with the expression of tumor-associated Wnt-targets(c-Myc, CyclinD1, Matrix Metalloproteinase 7), tumor proliferation, angiogenesis and a poor prognosis factor in NSCLC[11].