RNASEH2C and Aicardi-Goutieres syndrome: Mutations in three genes encoding the ribonuclease H2 enzyme complex, RNASEH2A on 19p13.13, RNASEH2B on 13q14.3, and RNASEH2C on 11q13.2, have also been described in the pathogenesis of AGS (Crow et al., 2006b).