The activation of caspase-3 and -7 activities in treated cancer cells during apoptosis results in: (1) inactivation of enzyme poly (ADP-ribose) polymerase or PARP, and (2) activation of caspase activated DNase (CAD), subsequently causing DNA fragmentation, which is one of characteristics of apoptosis [42], [43]. The gene discussed is CASP3; the disease is cancer.