Significant overexpression of the oncogenic miR-17-92 cluster of miRNAs occurs in lung cancer cell lines and tumours [18], where miR-17-92 miRNAs are upregulated by oncogenic c-Myc and act as part of a regulatory network balancing cell death and proliferation with c-Myc and E2F1 [19], [20], [21]. This evidence concerns the gene MYC and neoplasm.