There was a significant positive correlation, corrected for age, and gender, between IL-6 and diabetes duration (r = 0.29; p = 0.027), hypertension (r = 0.28; p = 0.030), dyslipidaemia (r = 0.25; p = 0.037), mycroalbuminuria (r = 0.29; p < 0.05), retinopathy (r = 0.26; p = 0.021), PAD (r = 0.30; p < 0.05) previous TIA/Stroke (r = 0.32; p < 0.0001), neuropathy (r = 0.34; p < 0.0001, diabetic foot grade, (r = 0.30; p < 0.0001)(see table 3). This evidence concerns the gene IL6 and diabetes mellitus.