NOS3 and preeclampsia: On the basis of these limited and conflicting studies, we designed this study to evaluate more systematically the contribution of maternal, paternal, and fetal components for the risk of preeclampsia, by selecting three gene polymorphisms, affecting the activity of biotransformation enzymes, such as GSTP1 and eNOS, and the endothelial function, such as LPL, in an ethnic population (i.e. Greek) never analyzed previously by this comprehensive approach.