To this end, and based on previous data, we designed a case–control study to evaluate the contribution of maternal and paternal–fetal components for the risk of preeclampsia, by analyzing the effects on preeclampsia risk of the three relatively common polymorphisms of the GSTP1, eNOS, and LPL genes in a cohort of preeclamptic and normal control trios (mother, father, and child) belonging to a different ethnic population (i.e. Greek) never analyzed previously by this approach. This evidence concerns the gene GSTP1 and preeclampsia.