RBFOX3 and ischemia: As shown in Fig. 4A, the results revealed that NeuN staining was high in the hippocampal CA1 region in sham (non-ischemic) animals (Fig. 4A, panel a), while ischemia/reperfusion and scrambled-tat injected control groups (Fig. 4A, panels b,c, respectively) showed a distinct loss of NeuN-stained neurons in the CA1 region 7 d after ischemia.