Molecular studies in multiple myeloma [11], lymphoma [12], breast [13], pancreatic [14], prostate cancer [15], head and neck squamous cell carcinoma [16], and colon [17] and bladder cancer [18] have demonstrated that NFκB may have a critical role in cancer development and chemoresistance [19]. The gene discussed is NFKB1; the disease is urinary bladder cancer.