In a tumor series from 26 melanoma patients, a strong correlation was noted between EMMPRIN and VEGFR-2 transcript levels, measured using qRT-PCR analysis, (Spearman r = 0.82 and r = 0.75 for relative expression to the housekeeping gene transcripts β2 microglobulin and PPIA respectively; both p<0.05). This evidence concerns the gene HLA-G and neoplasm.