CD8A and Familial prostate cancer: We induced apoptotic death of LNCaP prostate cancer cells, and allowed them to be phagocytosed by autologous DCs generated from prostate cancer patients' peripheral blood monocytes; such DCs were previously shown to stimulate both CD8+ and CD4+ T cells in vitro[29], and in a B16 mouse melanoma model DCs cross-presenting apoptotic tumor were effective in preventing tumor growth (Blachere et al., unpublished data).