While additional studies will be required tobetter define the cell biological functions of MIP and PI(3,5)P2, we proposethat the MIP-PI(3,5)P2 signaling pathway is an important contributor for agingsarcopenia, and as such could be explored as a new therapeutic option for thetreatment of not only muscle myopathies, but also for aging sarcopenia. This evidence concerns the gene MIP and sarcopenia.