Gao et al in 2009 observed that increase in c-Myc in human P-493 B lymphoma cells and PC3 prostate cancer cells leads to suppression of miR-23a/b which in turn results in greater expression of their target protein, mitochondrial glutaminase, which is required for bioenergetics, nucleotide biosynthesis and redox homeostasis in cancer cells [40]. Here, MYC is linked to cancer.