CDC25B and esophageal squamous cell carcinoma: In addition, our results demonstrate that CDC25B autoantibodies were more prevalent in sera from patients with advanced ESCC than in sera from patients with early stage disease (P < 0.001) and that in the patients with clinical stage III-IV and N1 subgroup, CDC25B-Abs seronegative patients survived longer than CDC25B-Abs seropositive patients.