DRD2 and schizophrenia: As shown in Figure 1A-B, the expression level of D2R dimers exhibited a significant increase (277.7 ± 33.6%) in the postmortem striatal sections of schizophrenia patients (n = 15, p < 0.001), whereas the expression of D2R monomers showed a substantial decrease (69.3 ± 7.3%, Figure 1A, C).