BRCA1 and neoplasm: In fact, there were a total of 22 proteins identified that relate, in some way, to the DNA damage response or to DNA repair including but not limited to: Rad50 (known [66], HR), BRCA1 (known [40]), tumor suppressor/genome surveillance), Ku86 (known [67], NHEJ), MSH2 and MSH3 (mismatch repair), and DDB1 (nucleotide excision repair).