In addition, it has been found that Bmi-1 is overexpressed in a variety of human cancers, such as mantle cell lymphomas[18], non-small cell lung cancer[19], B-cell non-Hodgkin's lymphoma[20], breast cancer[21], colorectal cancer[22], prostate cancer[23], nasopharyngeal carcinoma[16] and gastric carcinoma[24]. This evidence concerns the gene BMI1 and B-cell non-Hodgkin lymphoma.