We have also screened 10 Chinese families with various clinical arrhythmias, including 3 with LQTS, 2 with Brugada syndrome, 3 with sudden death syndrome, and 2 with Sick Sinus syndrome for mutations in KCNQ1, KCNH2, SCN5A, KCNE1 and KCNE2. The gene discussed is KCNH2; the disease is cardiac arrhythmia.