Two earlier LQTS-variant databases have been set up, one of which collected 232 mutations and 27 polymorphisms through 2003 (including KCNQ1, KCNH2, SCN5A, KCNE1 and KCNE2) (http://www.ssi.dk/graphics/html/lqtsdb/lqtsdb.htm); the other database collected over 798 mutations and 122 polymorphisms through 2007 (including LQT1-LQT9) (http://www.fsm.it/cardmoc/). Here, CAV3 is linked to familial long QT syndrome.