PDE5A and pulmonary arterial hypertension: In patients taking vasoactive medications, the most common treatments were: phosphodiesterase type 5 (PDE5) inhibitors, sildenafil (4 lSSc-PAH and 1 lSSc-noPAH patient) and tadenafil (1 lSSc-PAH patient); epoprostenol (3 lSSc-PAH patients and 1 lSSC-NoPAH patient); and nifedipine (9 lSSc-NoPAH patients).