Focused pathway analysis (using GO, KEGG, Biocarta and Panther databases) of the predicted miR-200 family targets that are consistently upmodulated in ULMs including patient B4 (Table S3) implicates categories of regulation of transcription proliferation and cell cycle control, actin cytoskeleton and adherens, tight, gap and focal adhesion junction remodeling, as well as cancer related signaling pathways (MAPK, RAS, WNT, NOTCH, TGF-β, VEGF). The gene discussed is VEGFA; the disease is cancer.