RHD and thalassemia: Anti-K in 41 (72%) patients and anti-E in 26 (45.6%) were reported.[13] In another study, Sirchia et al. collected clinical and laboratory data on Italian thalassemia major patients and detected 136 alloantibodies in 74 thalassemia patients that were against the antigens of the Rh, Kell, Kidd, and Duffy systems.[16]