H6PD and anemia: A particular condition called glucose-6-phosphate dehydrogenase deficiency, an X-linked recessive hereditary disease, is characterized by abnormally low levels of glucose-6-phosphate dehydrogenase enzyme (abbreviated G6PD or G6PDH).[5, 6] It is a metabolic enzyme involved in the pentose phosphate pathway, especially important in red blood cell metabolism.[7] Individuals with the disease may exhibit non-immune hemolytic anemia in response to a number of causes; develop anemia, jaundice and symptoms of hemolysis especially when there is a positive family history.