T3 treatment decreased the expression of miR-206 by roughly 50% (p<0.05) in miR-206 transfected AML 12 cells (Fig. 4C), while the expression of target genes Gpd2 and Mup1, but not Nrp1, significantly increased (Fig. 4D). The gene discussed is NRP1; the disease is acute myeloid leukemia.