We examined whether the influence of p-AMPK expression on colorectal cancer-specific survival was modified by any of the other variables including sex, age, BMI, family history of colorectal cancer, tumour location, stage, tumour grade, CIMP, MSI, BRAF, KRAS, PIK3CA, LINE-1 methylation, TP53 and FASN. The gene discussed is TP53; the disease is colorectal cancer.